Note: For more information refer to the monograph: Glucocorticoids, General Information or to the manufacturer’s product information.
Chemistry - Triamcinolone acetonide, a synthetic glucocorticoid, occurs as slightly odorous, white to cream-colored, crystalline powder with a melting point between 290 - 294°C. It is practically insoluble in water, very soluble in dehydrated alcohol and slightly soluble in alcohol. The commercially available sterile suspensions have a pH range of 5-7.5.
Storage/Stability/Compatibility - Triamcinolone acetonide products should be stored at room temperature (15-30°C); the injection should be protected from light.
For glucocorticoid effects:
a) 0.1 - 0.2 mg/kg IM or SQ; 3 - 6 mg subconjunctivally. (Robinson 1987)
b) 0.011 - 0.022 mg/kg PO bid;
0.011 - 0.022 mg/kg IM or SQ;
6 - 18 mg intra-articularly or intrasynovially, may repeat after 3-4 days; (Package inserts; Vetalog® Powder and Injection—Solvay)
Dosage Forms/Preparations/Approval Status/Withdrawal Times - All require a prescription (Rx).
Veterinary-Approved Products: Note: marketing status of oral preparations is in question.
Triamcinolone Tablets 0.5 mg, 1.5 mg; Vetalog® Tablets (Fort Dodge), generic. Approved for use in dogs and cats
Triamcinolone Acetonide Oral Powder 15 gram packets containing 10 grams of triamcinolone acetonide.; Vetalog® Oral Powder (Fort Dodge). Approved for use in horses.
Triamcinolone acetonide suspension for injection 2 mg/ml; 6 mg/ml ; Vetalog® Parenteral Veterinary (Fort Dodge); Generic. (Rx). Approved for use in dogs, cats, and horses.
Human-Approved Products include:
Triamcinolone Tablets 1 mg, 2 mg, 4 mg, 8 mg; Aristocort® (Fujisawa); Generic (Rx)
Triamcinolone Oral Syrup 4 mg/5ml Kenacort® (Apothecon); (Rx)
Triamcinolone Acetonide Sterile Suspension for injection 3 mg/ml, 10 mg/ml, 40 mg/ml; many tradenames; Generic, (Rx)
Many topical preparations are available, alone and in combination with other agents and inhaled products are also approved.
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